immunology
Stem Cells of the Eye
Stem Cells of the Eye Introduction Two prerequisites are essential for good vision. The first is a clear optical focusing system. The main components of this (the cornea, lens and intraocular fluids) are designed to bring vis…
immunology
Solute Transport
SOLUTE TRANSPORT Transport proteins in the cell membranes of the nephron mediate the reabsorption and secretion of solutes and water transport in the kidneys. Acquired defects in transport proteins are the cause of many ki…
pharmacology
Acyclovir (topical, oral and parentral }
Acyclovir (topical, oral and parentral) MOA 1) A guanosine analogue, activated by viral thymidine kinase into Acyclo GMP. 2) Then converted by human cellular kinase into Acyclo GTP (active form). 3) AcycloGTP inhibits viral …
pharmacology
Antifungal Amphotericin B , side effects , use , MOA
Amphotericin B mechanism of actions Tightly and selectively bind to ergosterol in the plasma membranes ➔ formation of artificial pores which disrupt membrane function. ✓ Eit…
pharmacology
Lipid
Lipids are water-insoluble (nonpolar) molecules that are soluble in weakly polar or nonpolar solvents such as chloroform. The most important function that lipids perform for all kinds of cells stems from their ability to form sheetli…
cell cell interaction
Interaction between T-cell and antigen-presenting cell
Interaction between T-cell and antigen-presenting cell cell cell interaction stepS: . A. Molecules Involved in Interactions between T Cells and APCs Several adhesion and acces…
fundamental principles
The Phagocyte System
The Phagocyte System Monocytes and Dendritic Cells A. The Phagocyte System Granulocytes. monocytes, and dendritic cells (DCs) have phagocytic capabilities (from the Greek word phagein to eat). They all derive from bloo…