clinical immunology
Immunotherapeutic strategies (2)
Immunotherapeutic strategies (2) Tumor immunity A. Production of Engineered Tumor-specific TCRs Many tumors are extensively infiltrated by lymphocytes. Tumor infiltrating lymphocytes (TIL) used to be removed from surgical spec…
clinical immunology
Immunotherapeutic strategies (1)
Immunotherapeutic strategies (1) tumor immunology A. Enhancement of Nonspecific Immunit y Around the end of the 19th century. the American surgeon William Coley began to inject cancer patients with tumor cell lysates t…
clinical immunology
Tumor escape mechanisms of tumor antigen
Tumor escape mechanisms of tumor antigen tumor immunity A. Tumor Antigens Ideally. a tumor antigen should be expressed only by tumor cells and not by normal cells in order to be recognized as foreign by the immune system. In re…
clinical immunology
Detection and identification of tumor antigen
detection and identification of tumor antigen tumor immunology The question of whether immunosurveillance against tumors truly exists is still unsolved. Bacteria and viruses. which…